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Mupirocin is used as a topical treatment for bacterial skin infections (for example, boils, impetigo, or open wounds), which are typically due to infection by Staphylococcus aureus or Streptococcus pyogenes. It is also useful in the treatment of superficial methicillin-resistant Staphylococcus aureus (MRSA) infections. [14]
The most common treatment options of intertrigo complicated with secondary bacterial infection such as group A beta-hemolytic streptococcus are topical mupirocin (bactroban), erythromycin, low potency topical steroids like hydrocortisone 1% cream, and oral antibiotics (such as oral penicillin, cephalexin, ceftriaxon, cefazolin, and clindamycin).
Impetigo is a contagious bacterial infection that involves the superficial skin. [2] The most common presentation is yellowish crusts on the face, arms, or legs. [2] Less commonly there may be large blisters which affect the groin or armpits. [2] The lesions may be painful or itchy. [3] Fever is uncommon. [3]
In skin infections and secondary infection sites, topical mupirocin is used successfully. For bacteremia and endocarditis, vancomycin or daptomycin is considered. For children with MRSA-infected bone or joints, treatment is individualized and long-term.
Oral antimicrobial treatment for active infection is commonly done with the use of mupirocin, linezolid, quinupristin, rifampicin or vancomyocin are possible treatments. [42] [43] Hand washing, sterilizing equipment and hygiene practices should be implemented to decrease the spread of Staphylococcus infections. [20] [43]
Urinary tract infections, bacterial prostatitis, community-acquired pneumonia, bacterial diarrhea, mycoplasmal infections, gonorrhea: Nausea (rare), irreversible damage to central nervous system (uncommon), tendinosis (rare) Inhibits the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription ...
Treatment typically involves antibiotics for bacterial infections and antifungals for fungal infections. If there is pus formation, incision and drainage may be necessary. [2] Paronychia is commonly mistakenly used interchangeably with herpetic whitlow or felon, which are distinct conditions. [2]
By culturing P. fluorescens, mupirocin (an antibiotic) can be produced, which has been found to be useful in treating skin, ear, and eye disorders. [23] Mupirocin free acid and its salts and esters are agents currently used in creams, ointments, and sprays as a treatment of methicillin-resistant Staphylococcus aureus infection.
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