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By 2007, the ketogenic diet was available from around 75 centres in 45 countries, and less restrictive variants, such as the modified Atkins diet, were in use, particularly among older children and adults. The ketogenic diet was also under investigation for the treatment of a wide variety of disorders other than epilepsy. [1]
A few cases have shown that patients were able to lessen their attacks with a high carbohydrate snack. A new approach to managing PED is the ketogenic diet, which alters the primary cerebral energy metabolism from glucose to ketone bodies. Reports have shown that the ketonic diet protects against seizures in epilepsy. [2]
The ketogenic diet was a popular treatment for pediatric epilepsy prior to the discovery of anti seizure medications. [38] The Modified Atkins Diet (MAD) is a low carbohydrate diet which has caused reductions in seizure frequency and severity, though not as effectively as the ketogenic diet. [26]
Ketogenic diet may be effective as second-line therapy for treatment-resistant cases. Neurosurgery may be indicated in certain cases. [2] [7] Epileptic spasms are commonly classified as symptomatic when a potential cause can be identified, or as cryptogenic if not (though these designations are used inconsistently). [2]
After one year on the ketogenic diet, the success rate (seizure reduction over 50%) is between 30 and 50% and the dropout rate is around 45%. [32] [33] Although the ketogenic diet can be very effective, some families report that it's not compatible with daily life given its restrictive nature. It can be especially difficult for adolescents to ...
The ketogenic diet is a high fat, low carbohydrate diet reserved for intractable childhood epilepsies. There are no published reports on the use of the ketogenic diet in patients with ring chromosome 20 syndrome. However, its efficacy and safety are well established in other difficult to control epilepsy syndromes.
The ketogenic diet may also influence neurotransmitters like dopamine and serotonin, which regulate mood, and the gut microbiome, which affects behavior and stress response, Sawhne explained.
The ketogenic diet consists of a high-fat, low-carbohydrate diet, and has shown good results in patients whose epilepsy has not responded to medications and who cannot receive surgery. The vagus nerve stimulator is a device that can be implanted into patients with epilepsy, especially that which originates from a specific part of the brain ...