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The lines are believed to trace the migration of embryonic cells. [4] They do not correspond to nervous, muscular, or lymphatic systems. The lines are not unique to humans and can be observed in other non-human animals with mosaicism. [9] [10] Alfred Blaschko is credited with the first demonstration of these lines in 1901. [11]
Metaphyseal tumors or lesions include osteosarcoma, chondrosarcoma, fibrosarcoma, osteoblastoma, enchondroma, fibrous dysplasia, simple bone cyst, aneurysmal bone cyst, non-ossifying fibroma, and osteoid osteoma. [5] One of the clinical signs of rickets that doctors look for is cupping and fraying at the metaphyses when seen on X-ray.
Pseudoachondroplasia. Leg radiographs depicting dysplastic distal femoral and proximal tibial epiphyses, and distal femoral metaphyseal broadening, cupping, irregularities (white arrows) and radiolucent areas especially medially. Note the metaphyseal line of ossification of the proximal tibias (blackarrows) and relative sparing of the tibial ...
The epiphyseal plate, epiphysial plate, physis, or growth plate is a hyaline cartilage plate in the metaphysis at each end of a long bone.It is the part of a long bone where new bone growth takes place; that is, the whole bone is alive, with maintenance remodeling throughout its existing bone tissue, but the growth plate is the place where the long bone grows longer (adds length).
In humans a similar mutation (G595E) has been associated with Schmid metaphyseal chondrodysplasia (SMCD), a relatively mild skeletal disorder that is also associated with dwarfism. [citation needed] The now extinct Ancon sheep was created by humans through the selective breeding of common domestic sheep with achondroplasia. The average-sized ...
Metaphyseal dysplasia, or Pyle disease, [3] is a disorder of the bones. It is a rare disease in which the outer part of the shafts of long bones is thinner than normal and there is an increased chance of fractures .
Growth arrest lines, also known as Harris lines, are lines of increased bone density that represent the position of the growth plate at the time of insult to the organism and formed on long bones due to growth arrest. They are only visible by radiograph or in cross-section. The age at which the lines were formed can be estimated from a radiograph.
An X-ray demonstrating the characteristic finding of lead poisoning in humans—dense metaphyseal lines: Specialty: Toxicology: Symptoms: Intellectual disability, abdominal pain, constipation, headaches, irritability, memory problems, inability to have children, tingling in the hands and feet [1] [2] Complications: Anemia, seizures, coma [1] [2 ...