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Using an oil-free face moisturizer in conjunction with erythromycin/benzoyl peroxide is recommended. Erythromycin/benzoyl peroxide was approved by the US Food and Drug Administration in 1984. [ 2 ] On March 30, 2004, a generic form of Benzamycin was released by pharmaceutical company Atrix Laboratories .
Erythromycin's elimination half-life ranges between 1.5 and 2.0 hours and is between 5 and 6 hours in patients with end-stage renal disease. Erythromycin levels peak in the serum 4 hours after dosing; ethylsuccinate peaks 0.5–2.5 hours after dosing, but can be delayed if digested with food. [39]
Erythromycin is a bacteriostatic macrolide antibiotic used to treat bacterial infections, including the inhibition of bacteria linked with acne, such Cutibacterium acnes. The mechanism of action is poorly understood.
Chemist Warehouse Group (trading as Sigma Healthcare Ltd) [3] is an Australian company operating a chain of retail chemists both locally and internationally. The company is one of Australia's largest chemist retailers with over 500 stores in Australia, [ 4 ] and employs over 20,000 staff. [ 5 ]
The primary role of pharmacies in the US is to safely and accurately fill prescriptions ordered by healthcare providers for patients. The pharmacy may receive a prescription in many ways, including a hardcopy, verbally over the phone, or electronically from the provider's electronic medical record system (EMR) is linked to the pharmacy. [5]
Saccharopolyspora erythraea produces the macrolide antibiotic erythromycin. [2] Cytochrome P450 eryF (CYP107A1) originally from the bacterium is responsible for the biosynthesis of the antibiotic by C6-hydroxylation of the macrolide 6-deoxyerythronolide B. [3] [4]
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
1952 – erythromycin, the first macrolide [2] 1954 – benzathine penicillin; 1955 – spiramycin; 1955 – tetracycline; 1955 – thiamphenicol; 1955 – vancomycin, the first glycopeptide; 1956 – phenoxymethylpenicillin; 1958 – colistin, the first polymyxin; 1958 – demeclocycline; 1959 – virginiamycin; 1960 – methicillin