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  2. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood thinners in use. People admitted to hospital requiring blood thinning were started on an infusion of heparin infusion, which thinned blood ...

  4. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes , which help keep the bite area unclotted long enough for the animal to obtain blood.

  5. Atherosclerosis: What Men Need to Know About Plaque ... - AOL

    www.aol.com/atherosclerosis-men-know-plaque...

    Atherosclerosis happens when a fatty substance called plaque builds up inside your arteries. There are typically few noticeable symptoms until the situation becomes dire and you experience ...

  6. Bayer's patent for blood thinner Xarelto invalid, UK ... - AOL

    www.aol.com/news/bayers-patent-blood-thinner...

    Bayer's patent covering its best-selling blood thinner Xarelto is invalid, London's High Court ruled on Friday in a blow to the German drugmaker. The company's blockbuster Xarelto drug generated ...

  7. File:Rivaroxaban structure.svg - Wikipedia

    en.wikipedia.org/wiki/File:Rivaroxaban_structure.svg

    The following other wikis use this file: Usage on fr.wikipedia.org Rivaroxaban; Usage on he.wikipedia.org ריברוקסבאן; Usage on hy.wikipedia.org

  8. Warfarin necrosis - Wikipedia

    en.wikipedia.org/wiki/Warfarin_necrosis

    The coagulation cascade.. Warfarin necrosis usually occurs three to five days after drug therapy is begun, and a high initial dose increases the risk of its development. [3]: 122 Warfarin-induced necrosis can develop both at sites of local injection and - when infused intravenously - in a widespread pattern.

  9. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Blood coagulation is a complex process by which the blood forms clots. It is an essential part of hemostasis and works by stopping blood loss from damaged blood vessels. [10] At the site of injury, where there is an exposure of blood under the endothelium, the platelets gather and immediately form a plug. That process is called primary hemostasis.

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