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2. Canagliflozin - Wikipedia

   en.wikipedia.org/wiki/Canagliflozin

   Canagliflozin, sold under the brand name Invokana among others, is a medication used to treat type 2 diabetes. [3] It is used together with exercise and diet. [3] It is not recommended in type 1 diabetes. [3] It is taken by mouth. [3] Common side effects include vaginal yeast infections, nausea, constipation, and urinary tract infections. [3]

3. SGLT2 inhibitor - Wikipedia

   en.wikipedia.org/wiki/SGLT2_inhibitor

   "FDA Drug Safety Communication: Interim clinical trial results find increased risk of leg and foot amputations, mostly affecting the toes, with the diabetes medicine canagliflozin (Invokana, Invokamet); FDA to investigate". U.S. Food and Drug Administration (FDA). 9 May 2017. "Warning use metformin in certain patients with reduced kidney function".

4. Johnson & Johnson Invokana PDUFA Preview - AOL

   www.aol.com/news/2013-03-20-johnson-johnson...

   It's almost here! Johnson & Johnson is eagerly awaiting a decision on its type 2 diabetes drug Invokana (canagliflozin) by the end of the month. The novel small molecule inhibits the SGLT2 protein ...

5. Discovery and development of gliflozins - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   Gliflozins are a class of drugs in the treatment of type 2 diabetes (T2D). They act by inhibiting sodium/glucose cotransporter 2 (SGLT-2), and are therefore also called SGLT-2 inhibitors. The efficacy of the drug is dependent on renal excretion and prevents glucose from going into blood circulation by promoting glucosuria. The mechanism of ...

6. 4 Ways to Prevent Muscle Loss on Ozempic & Other Weight ... - AOL

   www.aol.com/4-ways-prevent-muscle-loss-115800184...

   Other diabetes drugs, specifically sodium-glucose cotransporter 2 (SGLT2) inhibitors, can also lead to a reduction in lean mass. This includes canagliflozin (Invokana®) and dapagliflozin (Farxiga®).

7. Johnson & Johnson Waits for FDA Ruling on new Diabetes Drug - AOL

   www.aol.com/news/2013-03-28-johnson-johnson...

   From cutting edge science to the impact of Obamacare, from clinical trial results to FDA decisions, and from Bieber fever to hay fever, The Motley Fool's health-care team sits down each week to ...