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Topically applied sodium hyaluronate can facilitate the absorption of biomacromolecules, i.e. pharmaceuticals, and function like a nanocarrier. [16] Its effects on skin depend on the hyaluronate formulation and skin health: In barrier-deficient skin it restricted the delivery of biomacromolecules to the stratum corneum and viable epidermis.
Side effects are common and include loss of appetite, nausea, muscle pains, headache, and feeling tired. [2] [5] Serious side effect may include an irregular heartbeat or pancreatitis. [5] Sodium stibogluconate is less safe than some other options during pregnancy. [2] It is not believed to result in any problems if used during breastfeeding. [7]
Both local and systemic side effects can result from topical corticosteroid use, especially in prolonged treatment. [ 39 ] Local side effects can occur regularly from prolonged use, [ 45 ] which include skin atrophy (thinning), stretch marks , infections, lighter skin color, and sudden decrease in efficacy of the drug .
"This medication — which is a drug that inhibits sodium channels — works outside the brain on pain receptors," she noted. ... Certain medications can increase the risk of side effects and ...
However, when hydroxyzine is used in combination with pentosan polysulfate sodium it may be more effective than pentosan polysulfate sodium on its own, but large-scale studies are needed. [ 7 ] As a last-line treatment the calcineurin inhibitor cyclosporine A has been studied as a treatment for interstitial cystitis due to its immunosuppressive ...
Urea, also known as carbamide-containing cream, [clarification needed] is used as a medication and applied to the skin to treat dryness and itching such as may occur in psoriasis, dermatitis, or ichthyosis. [1] [2] [3] It may also be used to soften nails. [3] In adults side effects are generally few. [4] It may occasionally cause skin ...
COX-2 selective inhibitors have fewer gastrointestinal side effects, but promote thrombosis, and some of these agents substantially increase the risk of heart attack. As a result, certain COX-2 selective inhibitors—such as rofecoxib —are no longer used due to the high risk of undiagnosed vascular disease . [ 11 ]
Sodium citrate/sodium lauryl sulfoacetate/glycerol sold under the brandname Microlax and Micolette Micro enema, among others, is a small tube of liquid gel that is used to treat constipation. [ 1 ] The main active ingredients are sodium lauryl sulfoacetate (0.90% w/v ), sodium citrate (9.0% w/v ) and glycerol .