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(E)-10-hydroxynortiptyline blood level is comparable to that of nortriptyline, but its cerebrospinal fluid level, which is a close proxy of the brain concentration of a drug, is twice higher than nortriptyline's. Based on this, (E)-10-hydroxynortriptyline was suggested to significantly contribute to the antidepressant effects of amitriptyline ...
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The first six characters of the GPI define the therapeutic class code, the next two pairs the drug name, and the last four define route, dosage or strength. For example GPI 58-20-00-60-10-01-05 is for the drug nortriptyline HCl cap 10 mg (an antidepressant) and can be further classified as follows: [1]
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The Yellow Oval Room is an oval room located on the south side of the second floor in the White House, the official residence of the president of the United States. First used as a drawing room in the John Adams administration, it has been used as a library, office, and family parlor.
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Microsoft releases Windows 7, which, like Windows Vista, includes a full 64-bit version for AMD64/Intel 64 processors; most new computers are loaded by default with a 64-bit version. Microsoft also releases Windows Server 2008 R2 , which is the first 64-bit only server operating system.