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2. Sodium nitroprusside - Wikipedia

   en.wikipedia.org/wiki/Sodium_nitroprusside

   Nitroprusside is an inorganic compound with the chemical formula Na 2 [Fe(CN) 5 NO], usually encountered as the dihydrate, Na 2 [Fe(CN) 5 NO]·2H 2 O. [47] This red-colored sodium salt dissolves in water or ethanol to give solutions containing the free complex dianion [Fe(CN) 5 NO] 2−. Nitroprusside is a complex anion that features an ...

3. Nitrovasodilator - Wikipedia

   en.wikipedia.org/wiki/Nitrovasodilator

   Nitrovasodilators are prodrugs that donate NO by various mechanisms. Nitrates undergo chemical reduction, likely mediated by enzymes. Nitrates undergo chemical reduction, likely mediated by enzymes. Molsidomine and nitroprusside already contain nitrogen in the right oxidation state (+2) and liberate NO without the aid of enzymes.

4. Nitroglycerin (medication) - Wikipedia

   en.wikipedia.org/wiki/Nitroglycerin_(medication)

   [7] [8] [9] The drug nitroglycerin is a dilute form of the same chemical used as the explosive, nitroglycerin. [9] Dilution makes it non-explosive. [9] In 2022, it was the 196th most commonly prescribed medication in the United States, with more than 2 million prescriptions. [10] [11]

5. Nitroglycerin - Wikipedia

   en.wikipedia.org/wiki/Nitroglycerin

   Nitroglycerin (NG) (alternative spelling nitroglycerine), also known as trinitroglycerol (TNG), nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane, is a dense, colorless or pale yellow, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester.

6. Biological functions of nitric oxide - Wikipedia

   en.wikipedia.org/wiki/Biological_functions_of...

   Mechanism of action [ edit ] Nitric oxide is a cell signaling molecule produced by many cells of the body, and growing evidence suggests that the biological actions of the endocannabinoid system (ECS) may, in part, be mediated through its ability to regulate the production and/or release of nitric oxide. [ 82 ]

7. Simon's reagent - Wikipedia

   en.wikipedia.org/wiki/Simon's_reagent

   The reagent is typically provided in two parts: [2] [1] [3] A mixture of 2% sodium nitroprusside and 2% acetaldehyde in water (solution A) [4] A solution of 2% sodium carbonate in water (solution B) [4] Separate storage of the aldehyde and base are necessary to prevent aldol polymerisation of the aldehyde.

8. First pass effect - Wikipedia

   en.wikipedia.org/wiki/First_pass_effect

   First-pass metabolism may occur in the liver (for propranolol, lidocaine, clomethiazole, and nitroglycerin) or in the gut (for benzylpenicillin and insulin). [4] The four primary systems that affect the first pass effect of a drug are the enzymes of the gastrointestinal lumen, [5] gastrointestinal wall enzymes, [6] [7] [8] bacterial enzymes [5] and hepatic enzymes.

9. Alpha-4 beta-2 nicotinic receptor - Wikipedia

   en.wikipedia.org/wiki/Alpha-4_beta-2_nicotinic...

   The alpha-4 beta-2 nicotinic receptor, also known as the α4β2 receptor, is a type of nicotinic acetylcholine receptor implicated in learning, [1] consisting of α4 and β2 subunits. [2] It is located in the brain , where activation yields post- and presynaptic excitation , [ 2 ] mainly by increased Na + and K + permeability.