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Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
For the drugs administered by oral and dermal route, the units of threshold dose are mg/kg body-weight/day (dose of the drug in mg per body weight in kg per day) or ppm (parts per million), while the threshold dose of drugs by inhalation delivery has the unit of mg/L 6h/day (amount of drug in mg in 1L of air, for 6 hours per day). [8]
every day / daily quaque die q.h.s., qhs every night at bedtime quaque hora somni q.d.s, qds, QDS 4 times a day quater die sumendum q.i.d, qid 4 times a day quater in die q.h., qh every hour, hourly quaque hora q.o.d., qod every other day / alternate days quaque altera die q.p.m., qPM, qpm every afternoon or evening: quaque post meridiem q.s., qs
Cholinesterase inhibition was observed at all dose levels tested, and a NOAEL of 0.03 mg/kg/day estimated by dividing a LOAEL of 0.3 mg/kg/day by an uncertainty factor of 10. As with the acute RfD, the chronic RfD of 3×10 −4 mg/kg/day was determined by dividing this NOAEL by the inter- and intraspecies uncertainty factors.
every day (once daily) (preferred to "qd" in the UK [10]) o.d. oculus dexter: right eye o can be mistaken as an a which could read "a.d.", meaning right ear, confusion with "omni die" o.m. omni mane: every morning omn. bih. omni bihora: every 2 hours omn. hor. omni hora: every hour o.n. omni nocte: every night OPD once per day o.s.
The tonne (t) is an SI-compatible unit of mass equal to a megagram (Mg), or 10 3 kg. The unit is in common use for masses above about 10 3 kg and is often used with SI prefixes. For example, a gigagram ( Gg ) or 10 9 g is 10 3 tonnes, commonly called a kilotonne .
While MS-DOS and NT always treat the suffix after the last period in a file's name as its extension, in UNIX-like systems, the final period does not necessarily mean that the text after the last period is the file's extension. [1] Some file formats, such as .txt or .text, may be listed multiple times.
The system is based on LD50 determination in rats, thus an oral solid agent with an LD50 at 5 mg or less/kg bodyweight is Class Ia, at 5–50 mg/kg is Class Ib, LD50 at 50–2000 mg/kg is Class II, and at LD50 at the concentration more than 2000 mg/kg is classified as Class III. Values may differ for liquid oral agents and dermal agents. [1]