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Its deficiency can cause neurodevelopmental problems which can be partly reversible with early treatment. [27] Only a small subset of dementia cases have been found to be reversible with vitamin B 12 therapy. [28] Tinnitus may be associated with vitamin B 12 deficiency. [29] Vitamin B 12 deficiency may accompany certain eating disorders or ...
Blood tests may show fewer but larger red blood cells, low numbers of young red blood cells, low levels of vitamin B 12, and antibodies to intrinsic factor. [6] Diagnosis is not always straightforward and can be challenging. [10] Because pernicious anemia is due to a lack of intrinsic factor, it is not preventable. [11]
Vision loss in toxic and nutritional optic neuropathy is bilateral, symmetric, painless, gradual, and progressive. Dyschromatopsia, a change in color vision, is often the first symptom. Some patients notice that certain colors, particularly red, are less bright or vivid; others have a general loss of color perception.
Diamond-Blackfan Anemia is an example of a congenital bone marrow failure syndrome that primarily affects red blood cell production. In DBA, the erythroid cell lineage is more susceptible to cell death due to abnormal ribosome function. [4] This leads to a reduced population of red blood cell precursors and a resulting reticulocytopenia and anemia.
People with vision loss from ethambutol toxicity lose vision in both eyes equally. This initially presents with problems with colors (dyschromatopsia) and can leave central visual deficits. If vision loss occurs while using ethambutol, it would be best to discontinue this medication under a doctor's supervision.
A greyout is a transient loss of vision characterized by a perceived dimming of light and color, sometimes accompanied by a loss of peripheral vision. [1] It is a precursor to fainting or a blackout and is caused by hypoxia (low brain oxygen level), often due to a loss of blood pressure. Greyouts have a variety of possible causes:
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Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). [2]
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