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Fibrous dysplasia is a very rare [2] nonhereditary genetic disorder where normal bone and marrow is replaced with fibrous tissue, resulting in formation of bone that is weak and prone to expansion. As a result, most complications result from fracture , deformity, functional impairment, pain, and the impingement of nerves. [ 3 ]
It comprises a majority of the cases of fibrous dysplasia (approximately 70–80%). [2] It is a rare bone disease characterized by the replacement of normal elements of the bone by fibrous connective tissue, [3] which can cause very painful swellings and bone deformities, and make bone abnormally fragile and prone to fracture. [4]
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
Ido Simyoni has fibrous dysplasia, a rare condition where tumors form in bone. He needed 2 surgeries to reconstruct his forehead, prevent infection. At 15, tumors started growing into man’s skull.
Polyostotic fibrous dysplasia is a form of fibrous dysplasia affecting more than one bone. [2] Fibrous dysplasia is a disorder where bone is replaced by fibrous tissue, leading to weak bones, uneven growth, and deformity. [3] McCune–Albright syndrome includes polyostotic fibrous dysplasia as part of its presentation. [4]
Osteofibrous dysplasia is a rare, benign non-neoplastic condition with no known cause. It is considered a fibrovascular defect. Campanacci described this condition in two leg bones, the tibia and fibula, [1] and coined the term. This condition should be differentiated from nonossifying fibroma and fibrous dysplasia of bone.
Fibrodysplasia ossificans progressiva, a rare disease in which fibrous tissue becomes ossified; Fibromuscular dysplasia, a disease characterized by the fibrous thickening of the renal artery; Fibrous dysplasia, a disease that causes growths or lesions in one or more bones of the human body
Dysplasia is any of various types of abnormal growth or development of cells (microscopic scale) or organs (macroscopic scale), and the abnormal histology or anatomical structure(s) resulting from such growth. [1] Dysplasias on a mainly microscopic scale include epithelial dysplasia and fibrous dysplasia of bone.
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