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  2. Paroxysmal nocturnal hemoglobinuria - Wikipedia

    en.wikipedia.org/wiki/Paroxysmal_nocturnal...

    Danicopan, sold under the brand name Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement inhibitor which reversibly binds to factor D to prevent alternative pathway-mediated hemolysis and deposition of complement C3 proteins on red blood cells. The most common side effects include fever, headache, increased levels of liver enzymes (a sign ...

  3. Hemolysis - Wikipedia

    en.wikipedia.org/wiki/Hemolysis

    A red blood cell in a hypotonic solution, causing water to move into the cell A red blood cell in a hypertonic solution, causing water to move out of the cell. Hemolysis or haemolysis (/ h iː ˈ m ɒ l ɪ s ɪ s /), [1] also known by several other names, is the rupturing of red blood cells (erythrocytes) and the release of their contents into surrounding fluid (e.g. blood plasma).

  4. Dog skin disorders - Wikipedia

    en.wikipedia.org/wiki/Dog_skin_disorders

    Dog with atopic dermatitis, with signs around the eye created by rubbing. Atopy is a hereditary [3] and chronic (lifelong) allergic skin disease. Signs usually begin between 6 months and 3 years of age, with some breeds of dog, such as the golden retriever, showing signs at an earlier age.

  5. List of dog diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_dog_diseases

    Typical signs in dogs include sneezing, nasal discharge, bleeding from the nose, and ulcerations of the nose. [23] Pythiosis is a disease caused by a water mould of the genus Pythium, P. insidiosum. It occurs primarily in dogs and horses, but can also affect humans. In dogs it affects the gastrointestinal system and lymph nodes, and rarely the ...

  6. Dog health - Wikipedia

    en.wikipedia.org/wiki/Dog_health

    Cavalier King Charles Spaniel with bandaged foot A dog's injured leg. The health of dogs is a well studied area in veterinary medicine.. Dog health is viewed holistically; it encompasses many different aspects, including disease processes, genetics, and nutritional health, for example.

  7. Intravascular hemolysis - Wikipedia

    en.wikipedia.org/wiki/Intravascular_hemolysis

    Intravascular hemolysis describes hemolysis that happens mainly inside the vasculature. [1] As a result, the contents of the red blood cell are released into the general circulation, leading to hemoglobinemia [ 2 ] and increasing the risk of ensuing hyperbilirubinemia .

  8. Bleeding - Wikipedia

    en.wikipedia.org/wiki/Bleeding

    Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, vagina or anus, or through a puncture in the skin. Hypovolemia is a massive decrease in blood volume, and death by excessive loss of blood is referred to as exsanguination . [ 2 ]

  9. Canine discoid lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Canine_discoid_lupus_ery...

    The most common initial symptom is scaling and loss of pigment on the nose. The surface of the nose becomes smooth gray, and ulcerated, instead of the normal black cobblestone texture. Over time the lips, the skin around the eyes, the ears, and the genitals may become involved. [9] Lesions may progress to ulceration and lead to tissue ...