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  2. Virus crystallisation - Wikipedia

    en.wikipedia.org/wiki/Virus_Crystallisation

    Virus crystallisation is the re-arrangement of viral components into solid crystal particles. [1] The crystals are composed of thousands of inactive forms of a particular virus arranged in the shape of a prism. [2] The inactive nature of virus crystals provide advantages for immunologists to effectively analyze the structure and function behind ...

  3. History of virology - Wikipedia

    en.wikipedia.org/wiki/History_of_virology

    The importance of tobacco mosaic virus in the history of viruses cannot be overstated. It was the first virus to be discovered, and the first to be crystallised and its structure shown in detail. The first X-ray diffraction pictures of the crystallised virus were obtained by Bernal and Fankuchen in 1941.

  4. Jelly roll fold - Wikipedia

    en.wikipedia.org/wiki/Jelly_roll_fold

    The degree of structural similarity among double-jelly-roll virus capsids has led to the conclusion that these viruses likely have a common evolutionary origin despite their diversity in size and in host range; this has become known as the PRD1-adenovirus lineage (Bamfordvirae).

  5. Wendell Meredith Stanley - Wikipedia

    en.wikipedia.org/wiki/Wendell_Meredith_Stanley

    In 1948, he became Professor of Biochemistry at the University of California, Berkeley and built the Virus Laboratory and a free-standing Department of Biochemistry building, which is now called Stanley Hall. Stanley's work contributed to on lepracidal compounds, diphenyl stereochemistry and the chemistry of the

  6. Viral plaque - Wikipedia

    en.wikipedia.org/wiki/Viral_plaque

    Plaques from a virus isolated from a compost heap near UCLA. The bacterium is M. smegmatis. A viral plaque is a visible structure formed after introducing a viral sample to a cell culture grown on some nutrient medium. The virus will replicate and spread, generating regions of cell destruction known as plaques.

  7. Filamentous bacteriophage - Wikipedia

    en.wikipedia.org/wiki/Filamentous_bacteriophage

    The structures of the phage capsid and of some other phage proteins are available from the Protein Data Bank. [6] The single-stranded Ff phage DNA runs down the central core of the phage, and is protected by a cylindrical protein coat built from thousands of identical α-helical major coat protein subunits coded by phage gene 8.

  8. Viral evolution - Wikipedia

    en.wikipedia.org/wiki/Viral_evolution

    Viral evolution is a subfield of evolutionary biology and virology that is specifically concerned with the evolution of viruses. [1] [2] Viruses have short generation times, and many—in particular RNA viruses—have relatively high mutation rates (on the order of one point mutation or more per genome per round of replication).

  9. Viral vector - Wikipedia

    en.wikipedia.org/wiki/Viral_vector

    Structure of a virus, specifically the hepatitis C virus Viruses , infectious agents composed of a protein coat that encloses a genome , are the most numerous biological entities on Earth. [ 1 ] [ 2 ] As they cannot replicate independently, they must infect cells and hijack the host 's replication machinery in order to produce copies of ...