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  2. Omeprazole - Wikipedia

    en.wikipedia.org/wiki/Omeprazole

    Omeprazole was a subject of a patent litigation in the U.S. [66] The invention involved application of two different coatings to a drug in pill form to ensure that the omeprazole did not disintegrate before reaching its intended site of action in stomach. Although the solution by means of two coating was obvious, the patent was found valid ...

  3. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Most of these medications are benzimidazole derivatives, related to omeprazole, but imidazopyridine derivatives such as tenatoprazole have also been developed. [77] Potassium-competitive inhibitors such as revaprazan reversibly block the potassium-binding site of the proton pump, acting more quickly, but are not available in most countries.

  4. Omeprazole/amoxicillin/rifabutin - Wikipedia

    en.wikipedia.org/wiki/Omeprazole/amoxicillin/...

    Omeprazole: Proton-pump inhibitor: Amoxicillin: Penicillin-class antibacterial: ... is a fixed-dose combination medication used for the treatment of Helicobacter ...

  5. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]

  6. Are Dogs Lactose Intolerant? What Experts Advise About ...

    www.aol.com/dogs-lactose-intolerant-experts...

    Not all questions have simple, yes or no answers—including this one. While many dogs are lactose intolerant, many are not! Lactose intolerance develops as a dog grows up, so it can be impossible ...

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