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  2. Discovery and development of beta-blockers - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The consequences of treatment with β-blocker during pregnancy are disputable. Some studies report a connection between β-blocker treatment and small for-gestational-age (SGA) of newborns and pre-term birth, while others do not. [34] Based on meta-analyses, first trimester oral β-blocker use showed no increase in odds of major congenital ...

  3. Drugs in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_pregnancy

    Gestational diabetes is a form of diabetes that is first diagnosed during pregnancy and can accordingly cause high blood sugar that affects the woman and the baby. [9] In 10 - 20% of women whose diet and exercise are not adequate enough to control blood sugar, insulin injections may be required to lower blood sugar levels. [9]

  4. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    [5] [6] Risk in pregnancy has not been ruled out. [4] [7] It appears to be safe in breastfeeding. [8] The metabolism of metoprolol can vary widely among patients, often as a result of hepatic impairment [9] or CYP2D6 polymorphism. [10] Metoprolol was first made in 1969, patented in 1970, and approved for medical use in 1978.

  5. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Pregnancy. Although α-methyldopa is generally regarded as a first-line agent, labetalol and metoprolol are also acceptable. Atenolol has been associated with intrauterine growth retardation, as well as decreased placental growth and weight when prescribed during pregnancy.

  6. Maternal physiological changes in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Maternal_physiological...

    Overall, the systolic and diastolic blood pressure drops 10–15 mm Hg in the first trimester and then returns to baseline in the second half of pregnancy. [6] All of these cardiovascular adaptations can lead to common complaints, such as palpitations, decreased exercise tolerance, and dizziness.

  7. Pregnancy hormones - Wikipedia

    en.wikipedia.org/wiki/Pregnancy_hormones

    During pregnancy, the production of prolactin by the mother increases steadily, starting at 6–8 weeks of gestation and continuing until the end of the pregnancy. [32] Prolactin levels in the human fetal circulation see a gradual increase from around 30 weeks of gestation until birth. [ 32 ]

  8. Complications of pregnancy - Wikipedia

    en.wikipedia.org/wiki/Complications_of_pregnancy

    Most often, nausea and vomiting symptoms during pregnancy resolve in the first trimester, however, some continue to experience symptoms. Hyperemesis gravidarum is diagnosed by the following criteria: greater than 3 vomiting episodes per day, ketonuria, and weight loss of more than 3 kg or 5% of body weight.

  9. Signs and symptoms of pregnancy - Wikipedia

    en.wikipedia.org/.../Signs_and_symptoms_of_pregnancy

    Pregnancy symptoms may be categorized based on trimester as well as region of the body affected. Each pregnancy can be quite different and many people do not experience the same or all of the symptoms. If a person is concerned about their symptoms they should be encouraged to speak with an appropriate healthcare professional. [1]

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