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The monoclonal anti-IL6 antibody tocilizumab is another treatment option as effective as anakinra. [20] The condition "juvenile-onset Still's disease" is now usually grouped under juvenile rheumatoid arthritis. However, there are obvious similarities between the two conditions, [4] and there is some evidence that they may be closely related. [5 ...
Rheumatic fever primarily affects children between ages 5 and 17 years and occurs approximately 20 days after strep throat. In up to a third of cases, the underlying strep infection may not have caused any symptoms. [citation needed] The rate of development of rheumatic fever in individuals with untreated strep infection is estimated to be 3%.
Rheumatism [2] / ˈ r uː m ə t ɪ z əm / or rheumatic disorders are conditions causing chronic, often intermittent pain affecting the joints or connective tissue. [3] Rheumatism does not designate any specific disorder, but covers at least 200 different conditions, including arthritis and "non-articular rheumatism", also known as "regional pain syndrome" or "soft tissue rheumatism".
It is more common in older adults, with the mean age between 70 and 80 years in most studies. [4] [5] It occurs more often in men than in women with a 2:1 ratio. [4] [6] [7] It is unknown how common this condition is.
[12] [18] Overall arthritis becomes more common with age. [12] Arthritis is a common reason people are unable to carryout their work and can result in decreased ability to complete activities of daily living. [9] The term arthritis is derived from arthr-(meaning 'joint') and -itis (meaning 'inflammation'). [19] [20]
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [1] It typically results in warm, swollen, and painful joints. [ 1 ] Pain and stiffness often worsen following rest. [ 1 ]
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