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Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...
The process is highly regulated by cell adhesion molecules, particularly, the addressin also known as MADCAM1. This antigen is known for its role in tissue-specific adhesion of lymphocytes to high endothelium venules. [23] Through these interactions they play a crucial role in orchestrating circulating lymphocytes.
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The process of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of ...
Many studies have postulated that increased production of cell adhesion molecules (CAMs) on the vascular endothelium (blood vessel lining) plays a role in the development of arterial plaque, with the suggestion from both in vitro and in vivo studies that the CAM production is increased by dyslipidemia (abnormal lipid levels in the blood). [3]
Homophilic adhesion involves the immunoglobulin-like domains on the cell surface binding to the immunoglobulin-like domains on an opposing cell's surface while heterophilic adhesion refers to the binding of the immunoglobulin-like domains to integrins and carbohydrates instead. [21] Cell adhesion is a vital component of the body.
This complex interacts with fibrinogen and thus plays an important role in platelet aggregation and adhesion to endothelial surfaces. Activation of this complex initiates the platelet aggregation and the formation of primary platelet plug, a fibrin clot. The IIb / IIIa complex is a major platelet membrane component.
Cohesion, along with adhesion (attraction between unlike molecules), helps explain phenomena such as meniscus, surface tension and capillary action. Mercury in a glass flask is a good example of the effects of the ratio between cohesive and adhesive forces.
Adhesion is the tendency of dissimilar particles or surfaces to cling to one another. (Cohesion refers to the tendency of similar or identical particles and surfaces to cling to one another.) The forces that cause adhesion and cohesion can be divided into several types.