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Uromune, also known by its developmental code name MV-140, is a polyvalent bacterial vaccine which is used and is being developed for prevention of recurrent urinary tract infections (UTIs). [ 1 ] [ 2 ] [ 3 ] In clinical studies , it has been found to reduce total number of UTIs by about 70%, to increase UTI-free rates from around 25% to 57% ...
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder ( cystitis ) or urethra ( urethritis ) while upper urinary tract infections affect the kidney ( pyelonephritis ). [ 10 ]
Urinary bladder disease includes urinary bladder inflammation such as cystitis, bladder rupture and bladder obstruction (tamponade).Cystitis is common, sometimes referred to as urinary tract infection (UTI) caused by bacteria, bladder rupture occurs when the bladder is overfilled and not emptied while bladder tamponade is a result of blood clot formation near the bladder outlet.
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Urethral syndrome is defined as symptoms suggestive of a lower urinary tract infection but in the absence of significant bacteriuria with a conventional pathogen. [1] It is a diagnosis of exclusion in patients with dysuria and frequency without demonstrable infection. [2] In women, vaginitis should also be ruled out. [3]
The symptoms that a person may experience that cause the test to be requested may be blood in the urine, abdominal pain, abnormal kidney function tests, and frequent urinary tract infections (of which symptoms may include the need to pass urine frequently, pain on urination, and worsening urinary incontinence). [2]
Emphysematous cystitis is a rare type of infection of the bladder wall by gas-forming bacteria or fungi.The most frequent offending organism is E. coli.Other gram negative bacteria, including Klebsiella and Proteus are also commonly isolated.
NHS Direct was the health advice and information service provided by the National Health Service (NHS), established in March 1998. The nurse-led telephone information service provided residents and visitors in England with healthcare advice 24 hours a day, every day of the year through telephone contact on the national non-geographic 0845 46 47 number. [1]