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Amitriptyline is probably effective for the prevention of periodic migraine in adults. Amitriptyline is similar in efficacy to venlafaxine and topiramate but carries a higher burden of adverse effects than topiramate. [16] For many patients, even very small doses of amitriptyline are helpful, which may allow for minimization of side effects. [38]
Frunevetmab, sold under the brand name Solensia, is a monoclonal antibody used to treat pain associated with osteoarthritis in cats. [3] It is the first monoclonal antibody drug approved by the US Food and Drug Administration for animal use. [3] Frunevetmab is the international nonproprietary name. [5]
No seizures were seen within 16 hours of acepromazine administration in the 36 dogs that received the drug, and the seizures abated for 1.5 to 8 hours (n=6) or did not recur (n=2) in eight of 10 dogs that were actively seizing. Excitement-induced seizures were reduced for 2 months in one dog. [17]
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Elavil (amitriptyline) – a tricyclic antidepressant used as a first-line treatment for neuropathic pain; Eurodin, Prosom – a benzodiazepine derivative with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, commonly prescribed for short-term treatment of insomnia
Pizotifen is one of a range of medications used for this purpose, other options include propranolol, topiramate, valproic acid, cyproheptadine and amitriptyline.
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