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Cancer Associated Retinopathy (CAR) also known as Carcinoma Associated Retinopathy is an immune-mediated disease affecting the retina of the eye. It is a paraneoplastic type autoimmune retinopathy associated with cancer that can cause blindness. It can be seen in association with various types of cancers.
A major risk factor for AIR is a history of cancer, especially in paraneoplastic autoimmune retinopathy, where the autoimmune response is triggered by cancerous cells and cancer treatments. Cancer-associated retinopathy is commonly linked with cancers such as lung cancer and breast cancer, which trigger an autoimmune response due to malignant ...
Blue light, a type of high-energy light, is part of the visible light spectrum. High-energy visible light (HEV light) is short-wave light in the violet/blue band from 400 to 450 nm in the visible spectrum, which has a number of purported negative biological effects, namely on circadian rhythm and retinal health (blue-light hazard), which can lead to age-related macular degeneration.
Other sources restrict the use of the word to temporary, reversible vision loss, distinguishing it from permanent blindness in a hierarchy of effects: "when the eye perceives bright light one of four reactions may take place. These are, in order of increasing brightness: dazzle, after image formation, flash blindness, and irreversible damage.
Photic retinopathy is damage to the eye's retina, particularly the macula, from prolonged exposure to solar radiation or other bright light, e.g., lasers or arc welders.The term includes solar, laser, and welder's retinopathy and is synonymous with retinal phototoxicity. [1]
You may want to monitor your eyesight and watch for these symptoms. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ways to reach us ...
In patients with RVCL, the mutant TREX1 is found within the nucleus of the cell and associates with chromosomes. [2] [3] The resulting DNA damage, caused by a toxic mutated TREX1 protein, can cause premature senescence (aging) of cells, as well as heightened risk of early-onset breast cancer in women with RVCL. [2] [3]
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [3] [4] Cancer can be difficult to diagnose because its signs and symptoms are often nonspecific, meaning they may be general phenomena that do not point directly to a specific disease process.