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Maropitant (INN; [3] brand name: Cerenia, used as maropitant citrate , is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [4] [5] and in 2012, for cats. [6]
The most common cause is thyroid carcinoma, a malignant tumor. Signs include weight loss, increased appetite, and enlargement of the thyroid gland. [100] Hypothyroidism is the most common endocrine disease in dogs. It can be caused by autoimmune destruction (lymphocytic thyroiditis) or idiopathic atrophy of the thyroid gland. [101]
amitriptyline – tricyclic antidepressant used to treat separation anxiety, excessive grooming dogs and cats; amlodipine – calcium channel blocker used to decrease blood pressure; amoxicillin – antibacterial; apomorphine – emetic (used to induce vomiting) artificial tears – lubricant eye drops used as a tear supplement
Due to the indiscriminate nature of a dog's appetite, gastrointestinal upset is a frequent occurrence in dogs. The most common symptoms are anorexia, vomiting, and diarrhea. Foreign body ingestion can lead to acute obstruction of the gastrointestinal tract, a very dangerous condition. Acute pancreatitis can also result from dietary indiscretion.
frequent and/or excessive urination, known as polyuria, often requiring the dog to be let outside to urinate during the night, [47] greater than average appetite, increased appetite to abnormal levels, which is greater than the average appetite, a condition known as polyphagia., [45] [46]
Most of the other contraindications are avoiding cases where a potential side effect exacerbates a pre-existing condition: for example, because oclacitinib can cause lumps or tumors, it should not be used in dogs with cancer or a history of it; [15] because it is an immune system suppressant, it should not be used in dogs with serious infections.
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