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Structure of a G-quadruplex. Left: a G-tetrad. Right: an intramolecular G4 complex. [1]: fig1 In molecular biology, G-quadruplex secondary structures (G4) are formed in nucleic acids by sequences that are rich in guanine. [2] They are helical in shape and contain guanine tetrads that can form from one, [3] two [4] or four strands. [5]
DNAzyme research for the treatment of cancer is also underway. The development of a 10-23 DNAzyme that can block the expression of IGF-I (Insulin-like growth factor I, a contributor to normal cell growth as well as tumorigenesis) by targeting its mRNA could be useful for blocking the secretion of IGF-I from prostate storm primary cells ...
The 100 species with longest life-spans recorded and verified [1] This is a list of the longest-living biological organisms: the individual(s) (or in some instances, clones) of a species with the longest natural maximum life spans. For a given species, such a designation may include:
Experimental animals with genetic deficiencies in DNA repair often show decreased life span and increased cancer incidence. [13] For example, mice deficient in the dominant NHEJ pathway and in telomere maintenance mechanisms get lymphoma and infections more often, and, as a consequence, have shorter lifespans than wild-type mice. [62]
The water-accessible surface area of an IgG antibody. Immunoglobulin G (IgG) is a type of antibody.Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. [1]
In biology, a biological life cycle (or just life cycle when the biological context is clear) is a series of stages of the life of an organism, that begins as a zygote, often in an egg, and concludes as an adult that reproduces, producing an offspring in the form of a new zygote which then itself goes through the same series of stages, the ...
The Holdridge life zones system is a global bioclimatic scheme for the classification of land areas. It was first published by Leslie Holdridge in 1947, and updated in 1967. It is a relatively simple system based on few empirical data, giving objective criteria. [ 1 ]
The Sun, the star in the center of the Solar System to which the Earth is gravitationally bound, is an example of a G-type main-sequence star (G2V type). Each second, the Sun fuses approximately 600 million tons of hydrogen into helium in a process known as the proton–proton chain (4 hydrogens form 1 helium), converting about 4 million tons ...