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The pharmacology for ethcathinone appeared alongside other psychostimulants in a paper by Rothman and Baumann in 2006. [6] The predominant two modes of action for ethcathinone is as a moderately active releaser of noradrenaline (EC 50 = 99.3 nM); [6] however it is only a relatively weak inhibitor of dopamine reuptake (K i = 1,014 nM).
Amfepramone, also known as diethylpropion, is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant. [ 8 ] [ 9 ] It is used in the short-term management of obesity , along with dietary and lifestyle changes. [ 8 ]
[2] [3] It has been reported as a novel designer drug in several countries including the United Kingdom, [ 4 ] South Africa, [ 5 ] New Zealand, [ 6 ] the United States, [ 7 ] and Australia. [ 8 ] In 2018, N -ethylpentylone was the most common drug of the cathinone class to be identified in Drug Enforcement Administration seizures.
N-Ethylpentedrone (also known as α-ethylaminopentiophenone, α-EAPP, α-ethylamino-valerophenone, N-ethylnorpentedrone, and NEP) is a chemical compound of the substituted cathinone class. [4] Since the mid-2010s, NEP has been sold online as a designer drug .
[2] [3] It is a higher homolog of 4-methylpentedrone (4-MPD) with an ethyl group in place of the methyl group. 4-MEAP has been found in samples of drugs sold as 4-MPD. [4] In the United States, 4-MEAP is a Schedule I Controlled Substance. [5] [6]
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This is a list of aminorex analogues. Aminorex itself is a stimulant drug with a 5-phenyl-2-amino-oxazoline structure. It was developed in the 1960s as an anorectic, [1] [2] [3] but withdrawn from sale after it was discovered that extended use produced pulmonary hypertension, often followed by heart failure, which resulted in a number of deaths. [4]
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