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Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as effective antidepressants , especially for treatment-resistant depression and atypical depression . [ 1 ]
Compared to newer antidepressants, such as SSRIs and SNRIs, MAOIs are more likely to cause certain side effects and interactions. Side effects of MAOIs include the following: Dizziness. Headache ...
In addition, the nonselective MAOIs and the TCA SNRIs are widely believed to have an efficacy that is superior to the SSRIs normally picked as the first-line choice of agents for/in the treatment of MDD and related disorders. [31] The reason for this is based on the fact that SSRIs are safer than nonselective MAOIs and TCAs.
The improved safety and tolerability profile of the SSRIs in patients with MDD, compared with TCAs and MAOIs, represented yet another important advance in the treatment of depression. [ 23 ] Since the late 1980s, SSRIs have dominated the antidepressant drug market.
Full Antidepressants List: SSRIs, SNRIs, TCAs & Others. Antidepressants: the most common prescription medication among cool people like artists, fictional type As, film protagonists and yourself.
SSRIs may be used off-label for other conditions like eating disorders, body dysmorphic disorder and PE, to name a few. ... (MAOIs), St. John’s wort and other medications that increase serotonin ...
Taking monoamine oxidase inhibitors (MAOIs) in combination with SSRIs can be fatal, since MAOIs disrupt monoamine oxidase, an enzyme which is needed to break down serotonin and other neurotransmitters. Without monoamine oxidase, the body is unable to eliminate excess neurotransmitters, allowing them to build up to dangerous levels.
Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...