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Common side effects of antidepressant switching or discontinuation include: Returning symptoms of depression. Suicidal thoughts. Serotonin syndrome. Irritability. Flu-like symptoms. Dizziness.
There is support for the effectiveness of switching people to a different SSRI; 50% of people that were non-responsive after taking one SSRI were responsive after taking a second type. Switching people with treatment-resistant depression to a different class of antidepressants may also be effective.
Switching From Zoloft to Prozac: Final Thoughts. Thinking about swapping out your current medication for a new antidepressant is a big decision — but you don’t have to do it alone. With the ...
However, there are differences between TCA related antidepressants and classical TCAs in terms of side effect profiles and withdrawal when compared to SSRIs. [67] There is evidence a prominent side-effect of antidepressants, emotional blunting, is confused with a symptom of depression itself. The cited study, according to Professor Linda Gask was:
[83] [85] [86] Higher doses of antidepressants seem to be more likely to produce emotional blunting than lower doses. [83] It can be decreased by reducing dosage, discontinuing the medication, or switching to a different antidepressant that may have less propensity for causing this side effect. [83]
The world of depression treatment options is vast, varied and confusing at times. So many antidepressant medications, so many types of therapy, so many acronyms and so much information.
The American Psychiatric Association 2000 Practice Guideline advises that where no response is achieved within the following six to eight weeks of treatment with an antidepressant, switch to an antidepressant in the same class, and then to a different class. A 2006 meta-analysis review found wide variation in the findings of prior studies: for ...
There were three combination options (either an antidepressant or CBT added to citalopram), and four switch options (to either a different antidepressant or CBT). [1] Those who remitted or responded were offered 12-month naturalistic follow-up; non-remitters after two medication trials were encouraged to enter level 3; other non-remitters ...