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Phenylglycine is the organic compound with the formula C 6 H 5 CH(NH 2)CO 2 H. It is a non-proteinogenic alpha amino acid related to alanine, but with a phenyl group in place of the methyl group. It is a white solid. The compound exhibits some biological activity. [1]
N-phenylsydnone was first prepared in 1935 by John Campbell Earl and Alan W. Mackney [Wikidata] by cyclodehydration of N-Nitroso-N-phenylglycine with acetic anhydride. [4] Later work showed that this could be applied fairly generally to the nitrosamines of N-substituted amino acids. [2]
N-Phenylglycine is an organic compound with the formula C 6 H 5 NHCH 2 CO 2 H. This white solid achieved fame as the industrial precursor to indigo dye . [ 1 ] It is a non-proteinogenic alpha amino acid related to sarcosine , but with an N - phenyl group in place of N - methyl .
(S)-3,5-Dihydroxyphenylglycine or DHPG is a potent agonist of group I metabotropic glutamate receptors (mGluRs) mGluR1 and mGluR5.. DHPG was the first agonist shown to be selective for group I mGluRs. [1]
(RS)-MCPG is a phenylglycine derivative and a non-selective antagonist of group I and II metabotropic glutamate receptors (mGluRs). It has been used in long-term potentiation (LTP) as well as long-term depression (LTD) research and proved that certain LTP and LTD pathways depend on mGluRs.
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The list was consolidated and republished in Directive 2001/59/EC, [1] where translations into other EU languages may be found. These risk phrases are used internationally, not just in Europe, and there is an ongoing effort towards complete international harmonization using the Globally Harmonized System of Classification and Labelling of ...