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Oxycodone/paracetamol, sold under the brand name Percocet among others, is a fixed-dose combination of the opioid oxycodone with paracetamol (acetaminophen), used to treat moderate to severe pain. [1] In 2022, it was the 98th most commonly prescribed medication in the United States, with more than 6 million prescriptions. [2] [3]
Actavis Generics [1] (formerly known as Watson Pharmaceuticals and Actavis plc, prior to the acquisition of Irish-based Allergan, Inc.) is a global pharmaceutical company focused on acquiring, developing, manufacturing and marketing branded pharmaceuticals, generic and over-the-counter medicines, and biologic products.
Pentazocine, [3] sold under the brand name Talwin among others, is a painkiller used to treat moderate to severe pain. It is believed to work by activating (agonizing) κ-opioid receptors (KOR) and μ-opioid receptors (MOR).
After a dose of conventional (immediate-release) oral oxycodone, the onset of action is 10 to 30 minutes, [10] [8] and peak plasma levels of the drug are attained within roughly 30 to 60 minutes; [10] [8] [73] in contrast, after a dose of OxyContin (an oral controlled-release formulation), peak plasma levels of oxycodone occur in about three ...
Oral hydrocodone has a mean equivalent daily dosage (MEDD) factor of 0.4, meaning that 1 mg of hydrocodone is equivalent to 0.4 mg of intravenous morphine. However, because of morphine's low oral bioavailability , there is a 1:1 correspondence between orally administered morphine and orally administered hydrocodone.
Tetrachloroethylene, also known as perchloroethylene [a] or under the systematic name tetrachloroethene, and abbreviations such as perc (or PERC), and PCE, is a chlorocarbon with the formula Cl 2 C=CCl 2. It is a non-flammable, stable, colorless and heavy liquid widely used for dry cleaning of fabrics.
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An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]