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[3] [17] The inflammation can lead to the formation of scar tissue and adhesion that can make the spinal nerves "stick" together, a condition where such tissue develops in and between the leptomeninges - between dura and arachnoid or pia and arachnoid. [17] This condition can be very painful, especially when progressing to adhesive arachnoiditis.
Symptoms are pain or dysthesias (abnormal sensation) in the buttocks, hip, and posterior thigh with or without radiating leg pain. Patients often report pain when sitting. [ 1 ] The two most common causes are piriformis syndrome and fibrovascular bands (scar tissue), but many other causes exist. [ 2 ]
Scar tissue can feel like hard, flat lumps directly under the skin. Painful arousals. Pain occurs in about 20 to 70 percent of men with Peyronie’s disease during the acute phase.
There is excessive scar tissue formation within the joint and/or surrounding soft tissues leading to painful restriction of joint motion that persists despite physical therapy and rehabilitation. The scar tissue may be located inside the knee joint or may involve the soft tissue structures around the knee joint, or both locations.
Piriformis syndrome is often left undiagnosed and mistaken with other pains due to similar symptoms with back pain, quadriceps pain, lower leg pain, and buttock pain. These symptoms include tenderness, tingling and numbness initiating in low back and buttock area and then radiating down to the thigh and to the leg. [72]
Tethered spinal cord syndrome may go undiagnosed until adulthood, when sensory, motor, bowel, and bladder control issues emerge. This delayed presentation of symptoms relates to the degree of strain on the spinal cord over time. [5] Tethering may also develop after spinal cord injury. Scar tissue can block the flow of fluids around the spinal cord.
The healing of trauma to the outer anulus fibrosus may also result in the innervation of the scar tissue and pain impulses from the disc, as these nerves become inflamed by nucleus pulposus material. Degenerative disc disease can lead to a chronic debilitating condition and can reduce a person's quality of life.
Clavus papillari – a painful corn surrounded by a white border, which is either bruised or gelatinous tissue Clavus neurofibrosus (or fibrosus) – an old, deep scarred corn (in a crater with a white, sometimes macerated border) that is traversed by nerves and connective tissue, thought to be scar tissue caused by chronic low-grade inflammation.