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MammaPrint is a prognostic and predictive diagnostic test for early stage breast cancer patients that assess the risk that a tumor will metastasize to other parts of the body. [1] It gives a binary result, high-risk or low-risk classification, and helps physicians determine whether or not a patient will benefit from chemotherapy.
The results aid physicians in deciding appropriate treatment for each patient. There are four breast cancer tests within the Symphony suite: MammaPrint , which assists physicians and patients in complex chemotherapy decisions by giving a clear and unambiguous high or low result of the risk of metastasis during the period when chemotherapy is ...
The plot visualizes the differences between measurements taken in two samples, by transforming the data onto M (log ratio) and A (mean average) scales, then plotting these values. Though originally applied in the context of two channel DNA microarray gene expression data, MA plots are also used to visualise high-throughput sequencing analysis ...
Ternary plots are tools for analyzing compositional data in the three-dimensional case. In population genetics , a triangle plot of genotype frequencies is called a de Finetti diagram . In game theory [ 2 ] and convex optimization , [ 3 ] it is often called a simplex plot.
The process of data exploration may result in additional data cleaning or additional requests for data; thus, the initialization of the iterative phases mentioned in the lead paragraph of this section. [31] Descriptive statistics, such as, the average or median, can be generated to aid in understanding the data.
Excel maintains 15 figures in its numbers, but they are not always accurate; mathematically, the bottom line should be the same as the top line, in 'fp-math' the step '1 + 1/9000' leads to a rounding up as the first bit of the 14 bit tail '10111000110010' of the mantissa falling off the table when adding 1 is a '1', this up-rounding is not undone when subtracting the 1 again, since there is no ...
This results in data points with low p values (highly significant) appearing toward the top of the plot. The x axis is the logarithm of the fold change between the two conditions. The logarithm of the fold change is used so that changes in both directions appear equidistant from the center.
Violin plots are similar to box plots, except that they also show the probability density of the data at different values, usually smoothed by a kernel density estimator.A violin plot will include all the data that is in a box plot: a marker for the median of the data; a box or marker indicating the interquartile range; and possibly all sample points, if the number of samples is not too high.