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Superoxide dismutase 2, mitochondrial (SOD2), also known as manganese-dependent superoxide dismutase (MnSOD), is an enzyme which in humans is encoded by the SOD2 gene on chromosome 6. [5] [6] A related pseudogene has been identified on chromosome 1. Alternative splicing of this gene results in multiple transcript variants. [5]
Superoxide dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O − 2) anion radical into normal molecular oxygen (O 2) and hydrogen peroxide (H 2 O 2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. [2]
The MM algorithm is an iterative optimization method which exploits the convexity of a function in order to find its maxima or minima. The MM stands for “Majorize-Minimization” or “Minorize-Maximization”, depending on whether the desired optimization is a minimization or a maximization.
The Lotka–Volterra system of equations is an example of a Kolmogorov population model (not to be confused with the better known Kolmogorov equations), [2] [3] [4] which is a more general framework that can model the dynamics of ecological systems with predator–prey interactions, competition, disease, and mutualism.