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Genetic testing is often done as part of a genetic consultation and as of mid-2008 there were more than 1,200 clinically applicable genetic tests available. [23] Once a person decides to proceed with genetic testing, a medical geneticist, genetic counselor, primary care doctor, or specialist can order the test after obtaining informed consent .
Color Data, a database containing aggregated genetic and clinical information from 50,000 individuals who took a Color test, [26] helps researchers and scientists identify genotype-phenotype correlations and novel variants for functional analysis, as well as enables data-driven drug discovery and development. It is the largest public database ...
The implications of genetic test results for other family members are important to consider in patients considering elective genetic testing. Unlike most other medical tests, genetic testing may reveal health information about the patient as well as his or her family members. [ 51 ]
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A patient's genome may include an inherited or random mutation which affects the probability of developing a disease in the future. [27] For example, Lynch syndrome is a genetic disease that predisposes patients to colorectal and other cancers; early detection can lead to close monitoring that improves the patient's chances of a good outcome. [39]
Oncogenomics is a sub-field of genomics that characterizes cancer-associated genes.It focuses on genomic, epigenomic and transcript alterations in cancer. Cancer is a genetic disease caused by accumulation of DNA mutations and epigenetic alterations leading to unrestrained cell proliferation and neoplasm formation.
The researchers found that “patients with (a) low Y chromosome gene expression score had significantly worse overall survival compared with those with higher expression,” the study said.
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