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Other treatment options include devices (such as vacuum erection devices), surgery (penile implants), testosterone replacement therapy (available as a gel, injection, patch and pellet) and ...
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Trimix is a combination of three drugs: alprostadil, papaverine, and phentolamine. These medications work in combination to increase blood flow to the penis, resulting in an erection. [1] [2] [3] Alprostadil is a prostaglandin vasodilator that allows more blood to flow into the area by relaxing the smooth muscle in the blood vessels of the penis.
However, all medications for ED have the potential to interact with other medications, including several prescription drugs for health conditions like hypertension (high blood pressure), heart ...
PDE5 inhibitors are contraindicated within 24 hours (or 48 hours with tadalafil) of taking alpha-blockers, soluble guanylate cyclase stimulators, or nitrate medications such as isosorbide mononitrate or isosorbide dinitrate. [1] Concurrent use of these medications can lead to life-threatening low blood pressure. [5]
Papaverine is used as an erectile dysfunction drug, alone or sometimes in combination. [6] [7] Papaverine, when injected in penile tissue, causes direct smooth muscle relaxation and consequent filling of the corpus cavernosum with blood resulting in erection. A topical gel is also available for ED treatment. [8]
Drugs called PDE5 inhibitors are commonly prescribed as a first line of treatment for ED. They work by inhibiting the enzyme phosphodiesterase-5 (PDE5) found in the smooth muscle cells of the ...
The term erectile dysfunction does not encompass other erection-related disorders, such as priapism. Treatment of ED encompasses addressing the underlying causes, lifestyle modification, and addressing psychosocial issues. [4] In many instances, medication-based therapies are used, specifically PDE5 inhibitors like sildenafil. [13]
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