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Management of GTN requires pathology review, treatment options and monitoring of hCG. Therefore, it can be treated with curettage, hysterectomy and single agent or multi agent chemotherapy. [ 4 ] Although this group of diseases are highly susceptible to chemotherapy, prognosis depends on the type of GTN and whether the tumor has spread to other ...
A placental site trophoblastic tumor is a monophasic neoplasm of the implantation site intermediate trophoblast, and usually a benign lesion, which comprises less than 2% of all gestational trophoblastic proliferations. Preceding conditions include molar pregnancy (5%).
The trophoblast (from Greek trephein: to feed; and blastos: germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. [ 1 ] They provide nutrients to the embryo and develop into a large part of the placenta .
Both are composed of intermediate trophoblast, but their morphological features and clinical presentation can differ significantly. Exaggerated placental site is a benign, non cancerous lesion with an increased number of implantation site intermediate trophoblastic cells that infiltrate the endometrium and the underlying myometrium .
4 Treatment. 5 Prognosis. 6 References. ... It is a trophoblastic tumor of neoplastic chorionic type associated with the intermediate trophoblast. Signs and symptoms
5T4 is an antigen expressed in a number of carcinomas. [7] It is an N-glycosylated transmembrane 72 kDa glycoprotein containing eight leucine-rich repeats. [6] 5T4 is often referred to as an oncofetal antigen due to its expression in foetal trophoblast (where it was first discovered) or trophoblast glycoprotein (TPBG).
Treatment for cardiovascular disease depends on which type you have and the severity of your condition. Let’s take a look at the different types of cardiovascular disease and what type of ...
It possesses an inner cell mass (ICM) also known as the embryoblast which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm. [1] [2] This layer surrounds the inner cell mass and a fluid-filled cavity or lumen known as the blastocoel. [3] In the late blastocyst, the trophectoderm is known as the ...