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  2. Self-complementary adeno-associated virus - Wikipedia

    en.wikipedia.org/wiki/Self-Complementary_Adeno...

    Self-complementary adeno-associated virus (scAAV) is a viral vector engineered from the naturally occurring adeno-associated virus (AAV) to be used as a tool for gene therapy. [1] Use of recombinant AAV (rAAV) has been successful in clinical trials addressing a variety of diseases. [ 2 ]

  3. Transgene (company) - Wikipedia

    en.wikipedia.org/wiki/Transgene_(company)

    Transgene was founded in 1979, on the initiative of Pierre Chambon and Philippe Kourilsky. Jean-Pierre Lecocq was the first Scientific Director of Transgene in 1980. [2] Dr Alessandro Riva, MD, joined Transgene in 2022 as Chairman of the Board of Directors. In May 2023 the board appointed him Chairman adn Chief Executive Officer of the company ...

  4. Adeno-associated virus - Wikipedia

    en.wikipedia.org/wiki/Adeno-associated_virus

    In-vivo studies indicate that AAV vectors interact with the Toll-like receptor (TLR)9- and TLR2-MyD88 pathways to trigger the innate immune response by stimulating the production of interferons. [102] It's shown that mice deficient in TLR9 are more receptive to AAV treatment and demonstrate higher levels of transgene expression [103]

  5. Are you ‘competent and caring?’ Then Elon Musk’s ... - AOL

    www.aol.com/news/competent-caring-then-elon-musk...

    Elon Musk’s Department of Government Efficiency has appealed to “competent” and “caring” people to join the cost-cutting team. Applications to join the billionaire’s newly formed ...

  6. R. Jude Samulski - Wikipedia

    en.wikipedia.org/wiki/R._Jude_Samulski

    He co-founded biotechnology companies active in gene therapy and AAV commercialization, [8] including AskBio (Asklepios BioPharmaceutical Inc.), a biotechnology company focused on AAV gene therapy, [9] [10] NanoCor Therapeutics, Inc. [11] Chatham Therapeutics, Inc. and Bamboo Therapeutics, Inc, spinoffs from Asklepios BioPharmaceutical Inc. [12] He was the director of the UNC School of ...

  7. Recombinant AAV mediated genome engineering - Wikipedia

    en.wikipedia.org/wiki/Recombinant_AAV_mediated...

    Recombinant adeno-associated virus (rAAV) based genome engineering is a genome editing platform centered on the use of recombinant AAV vectors that enables insertion, deletion or substitution of DNA sequences into the genomes of live mammalian cells.

  8. Gaza checkpoint to be staffed by scores of armed American ...

    www.aol.com/news/exclusive-inside-us-security...

    UG Solutions - a low-profile company founded in 2023 and based in Davidson, North Carolina - is offering a daily rate starting at $1,100 with a $10,000 adv Gaza checkpoint to be staffed by scores ...

  9. OpenAI clinches deal with Kakao, talks with SoftBank and ...

    www.aol.com/news/openai-kakao-jointly-develop-ai...

    SEOUL (Reuters) -OpenAI said on Tuesday it will develop artificial intelligence products for South Korea with chat app operator Kakao, unveiling a second major alliance with a high-profile Asian ...

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