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Two SSRIs, sertraline (Zoloft) and paroxetine (Paxil), are FDA-approved to treat PTSD. Other SSRIs are sometimes prescribed off-label to treat PTSD, meaning they’re used for something they’re ...
Taking monoamine oxidase inhibitors (MAOIs) in combination with SSRIs can be fatal, since MAOIs disrupt monoamine oxidase, an enzyme which is needed to break down serotonin and other neurotransmitters. Without monoamine oxidase, the body is unable to eliminate excess neurotransmitters, allowing them to build up to dangerous levels.
Compared to newer antidepressants, such as SSRIs and SNRIs, MAOIs are more likely to cause certain side effects and interactions. Side effects of MAOIs include the following: Dizziness. Headache ...
This includes post-traumatic stress disorder (PTSD), social anxiety disorder and obsessive-compulsive disorder (OCD). The most common SSRIs are: Fluoxetine (Prozac)
For example, cocaine, which non-selectively inhibits the reuptake of serotonin, norepinephrine, and dopamine, is an SRI but not an SSRI. SRIs are used predominantly as antidepressants (e.g., SSRIs, SNRIs, and TCAs), though they are also commonly used in the treatment of other psychological conditions such as anxiety disorders and eating disorders.
In addition, the nonselective MAOIs and the TCA SNRIs are widely believed to have an efficacy that is superior to the SSRIs normally picked as the first-line choice of agents for/in the treatment of MDD and related disorders. [31] The reason for this is based on the fact that SSRIs are safer than nonselective MAOIs and TCAs.
Post-traumatic stress disorder . Social anxiety disorder. SSRIs may be used off-label for other conditions like eating disorders, body dysmorphic disorder and PE, to name a few. ... (MAOIs), St ...
Most antidepressants will hinder the breakdown of serotonin, norepinephrine, and/or dopamine. A commonly used class of antidepressants are called selective serotonin reuptake inhibitors (SSRIs), which act on serotonin transporters in the brain to increase levels of serotonin in the synaptic cleft. [22]