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[14]: 69–75 [21] By 1899, Bayer had named it "Aspirin" and was selling it around the world. [16] Aspirin's popularity grew over the first half of the 20th century, leading to competition between many brands and formulations. [22] The word Aspirin was Bayer's brand name; however, its rights to the trademark were lost or sold in many countries ...
Despite this, some people believed that Germans put the Spanish flu bug in Bayer aspirin, causing the pandemic as a war tactic. [3]: 136–142 Newspaper ad for Bayer Aspirin from April 1918. The aspirin patent had expired, Bayer still had control over the Aspirin trademark, seen at the bottom of the ad, and a "patriotic" slogan to buy war bonds.
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The acutely toxic dose of aspirin is generally considered greater than 150 mg per kg of body mass. [12] Moderate toxicity occurs at doses up to 300 mg/kg, severe toxicity occurs between 300 and 500 mg/kg, and a potentially lethal dose is greater than 500 mg/kg. [13]
In 1904, Bayer received a trademark for the "Bayer Cross" logo, which was subsequently stamped onto each aspirin tablet, creating an iconic product that is still sold by Bayer. [ citation needed ] Other commonly known products initially commercialized by Bayer include heroin , phenobarbital , polyurethanes , and polycarbonates .
A caplet is a smooth, coated, oval-shaped medicinal tablet in the general shape of a capsule. Many caplets have an indentation running down the middle, so they may be split in half more easily. [ 5 ] Consumers have viewed capsules as the most effective way to take medication ever since they first appeared.
An enteric coating is a polymer barrier applied to oral medication that prevents its dissolution or disintegration in the gastric environment. [1] This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine). [2]
Encaprin was a brand of safety-coated aspirin capsules made by Procter & Gamble in the mid-1980s through its Norwich Eaton Pharmaceuticals division. In 1986, the brand was involved in a cyanide poisoning hoax, and its sales never recovered.
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