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This work is in the public domain in the United States because it is a work prepared by an officer or employee of the United States Government as part of that person’s official duties under the terms of Title 17, Chapter 1, Section 105 of the US Code.
In the Patient Zero study, the average length of time between sexual contact and the onset of symptoms was 10 + 1 ⁄ 2 months. [8] While Shilts' book does not make such an allegation, the rumour that Dugas was the principal disseminator of the virus became widespread. [15] In 1988, Andrew R. Moss published an opposing view in The New York ...
Abortive HIV infection occurs due to slowing of reverse transcription promoting cytosolic DNA accumulation. This viral DNA is sensed by gamma-interferon-inducible protein 16 ( IFI16 ), [ 11 ] which produces an innate immune response against the virus by activating caspase 1 in IFI16 inflammasomes and inducing pyroptosis , a highly inflammatory ...
Notable For Dummies books include: DOS For Dummies, the first, published in 1991, whose first printing was just 7,500 copies [4] [5] Windows for Dummies, asserted to be the best-selling computer book of all time, with more than 15 million sold [4] L'Histoire de France Pour Les Nuls, the top-selling non-English For Dummies title, with more than ...
Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was originally discovered (and initially referred to also as LAV or HTLV-III). It is more virulent, more infective, [99] and is the cause of the majority of HIV infections globally. The lower infectivity of HIV-2 as compared with HIV-1 implies that fewer people ...
The book was published shortly after Willner's medical license was revoked for, among other things, treating an AIDS patient with ozone therapy. [ 2 ] The following month, on October 28, 1994, in a press conference at a Greensboro, North Carolina hotel, Willner jabbed his finger with blood he said was from an HIV-infected patient.
Dual-tropic HIV-1 strains are thought to be transitional strains of HIV-1 and thus are able to use both CCR5 and CXCR4 as co-receptors for viral entry. The α-chemokine SDF-1, a ligand for CXCR4, suppresses replication of T-tropic HIV-1 isolates. It does this by down-regulating the expression of CXCR4 on the surface of HIV target cells. M ...
Alpha Books, publisher of the Complete Idiot's Guides, is a member of Penguin Group. It began as a division of Macmillan. Pearson Education acquired Macmillan General Reference (MGR) from Simon & Schuster in 1998 and retained the line while the rest of MGR was sold to IDG Books. [1] Alpha moved from Pearson Education to Penguin Group in 2003 ...