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  2. Reperfusion injury - Wikipedia

    en.wikipedia.org/wiki/Reperfusion_injury

    Reperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re-+ perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).

  3. Reperfusion therapy - Wikipedia

    en.wikipedia.org/wiki/Reperfusion_therapy

    Reperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack (myocardial infarction (MI)). Reperfusion therapy includes drugs and surgery. The drugs are thrombolytics and fibrinolytics used in a process called thrombolysis.

  4. Ischemia-reperfusion injury of the appendicular ...

    en.wikipedia.org/wiki/Ischemia-reperfusion...

    Ischemia-reperfusion (IR) tissue injury is the resultant pathology from a combination of factors, including tissue hypoxia, followed by tissue damage associated with re-oxygenation. IR injury contributes to disease and mortality in a variety of pathologies, including myocardial infarction , ischemic stroke , acute kidney injury , trauma ...

  5. Management of acute coronary syndrome - Wikipedia

    en.wikipedia.org/wiki/Management_of_acute...

    The concept of reperfusion has become so central to the modern treatment of acute myocardial infarction, that we are said to be in the reperfusion era. [ 53 ] [ 54 ] Patients who present with suspected acute myocardial infarction and ST segment elevation (STEMI) or new bundle branch block on the 12 lead ECG are presumed to have an occlusive ...

  6. Ischemia - Wikipedia

    en.wikipedia.org/wiki/Ischemia

    For frostbite injuries, limiting thawing and warming of tissues until warmer temperatures can be sustained may reduce reperfusion injury. Ischemic stroke is at times treated with various levels of statin therapy at hospital discharge, followed by home time, in an attempt to lower the risk of adverse events.

  7. Cerebral hyperperfusion syndrome - Wikipedia

    en.wikipedia.org/wiki/Cerebral_hyperperfusion...

    Cerebral hyperperfusion syndrome, also known as reperfusion syndrome, is a dysregulated state of cerebral blood flow following the restoration of arterial blood flow to the brain, usually following treatment of carotid artery stenosis. [1]

  8. Post-cardiac arrest syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-Cardiac_Arrest_Syndrome

    This reperfusion results in inflammatory injury through three overlapping mechanisms. Some complimentary combination of, first, mitochondrial damage and, second, endothelial activation , causes a release of reactive oxygen species (ROS), which initiates and/or exacerbates a pathophysiological inflammatory response.

  9. Human HGF plasmid DNA therapy - Wikipedia

    en.wikipedia.org/wiki/Human_HGF_plasmid_DNA_therapy

    [1] [2] After MI, the myocardium suffers from reperfusion injury which leads to death of cardiomyocytes and detrimental remodelling of the heart, consequently reducing proper cardiac function. [2] Transfection of cardiac myocytes with human HGF reduces ischemic reperfusion injury after MI. The benefits of HGF therapy include preventing improper ...