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  2. Lactic acidosis - Wikipedia

    en.wikipedia.org/wiki/Lactic_acidosis

    The symptoms are generally attributable to the underlying cause, but may include nausea, vomiting, shortness of breath, and generalised weakness. The diagnosis is made on biochemical analysis of blood (often initially on arterial blood gas samples), and once confirmed, generally prompts an investigation to establish the underlying cause to ...

  3. Wild-type transthyretin amyloid - Wikipedia

    en.wikipedia.org/wiki/Wild-Type_Transthyretin...

    The disorder typically affects the heart and its prevalence increases in older age groups. Men are affected much more frequently than women, [3] and up to 25% of men over the age of 80 may have evidence of WTTA. [4] Patients often present with increased thickness of the wall of the main heart chamber, the left ventricle.

  4. Pernicious anemia - Wikipedia

    en.wikipedia.org/wiki/Pernicious_anemia

    Pernicious anemia often presents slowly, and can cause harm insidiously and unnoticeably. Untreated, it can lead to neurological complications, and in serious cases, death. [19] The onset may be vague and slow and the condition can be confused with other conditions, and there may be few to many symptoms without anemia. [20]

  5. Coronary ischemia - Wikipedia

    en.wikipedia.org/wiki/Coronary_ischemia

    Certain individuals such as women, diabetics, and the elderly may present with more varied symptoms. [8] If blood flow through the coronary arteries is stopped completely, cardiac muscle cells may die, known as a myocardial infarction, or heart attack. [9] Coronary artery disease (CAD) is the most common cause of coronary ischemia. [7]

  6. Polycythemia vera - Wikipedia

    en.wikipedia.org/wiki/Polycythemia_vera

    In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [2] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.

  7. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    In older people, however, this difference becomes less pronounced: after the age of 80 years, new cases of CLL are diagnosed equally between men and women. [ 90 ] According to the American Cancer Society, they estimate that there will about 23,690 new cases of CLL with about 4,460 deaths from CLL in the United States throughout 2025. [ 19 ]

  8. Critical green inclusion - Wikipedia

    en.wikipedia.org/wiki/Critical_green_inclusion

    Critical green inclusions are a rare finding, and when found they are suggestive of a poor prognosis, hence the colloquial term death crystals.A 2018 review found that 56% of patients died shortly after the inclusions were first identified (usually within two weeks). [5]

  9. Normocytic anemia - Wikipedia

    en.wikipedia.org/wiki/Normocytic_anemia

    An acute loss of blood of a substantial volume; a decreased production of normal-sized red blood cells (e.g., anemia of chronic disease, aplastic anemia); an increased production of HbS as seen in sickle cell disease (not sickle cell trait); an increased destruction or loss of red blood cells (e.g., hemolysis, posthemorrhagic anemia ...