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While genetic mutations occur naturally in the wild, some breeders have come under fire for purposely creating “mutant” animals. In 2015, some South African breeders and ranchers made ...
This disaster made the environment highly mutagenic, leading to various evolutionary processes including, but not limited to, bottlenecks, directional selection, and higher rates of mutation resulting in evolutionary trajectories that differ from unexposed animals. [1]
In biology, and especially in genetics, a mutant is an organism or a new genetic character arising or resulting from an instance of mutation, which is generally an alteration of the DNA sequence of the genome or chromosome of an organism. It is a characteristic that would not be observed naturally in a specimen.
Types of mutations that can be introduced by random, site-directed, combinatorial, or insertional mutagenesis. In molecular biology, mutagenesis is an important laboratory technique whereby DNA mutations are deliberately engineered to produce libraries of mutant genes, proteins, strains of bacteria, or other genetically modified organisms.
If a transheterozygote inheriting two unknown recessive mutations continues to show the mutant phenotype, it can be concluded that both mutations must be in the same gene, because inheritance of just one recessive mutation in each of two different genes would result in an organism displaying the dominant wild type phenotype.
Hermann J. Muller (1890–1967), who was a 1946 Nobel Prize winner, coined the terms amorph, hypomorph, hypermorph, antimorph and neomorph to classify mutations based on their behaviour in various genetic situations, as well as gene interaction between themselves. [1] These classifications are still widely used in Drosophila genetics to ...
A de novo mutation (DNM) is any mutation or alteration in the genome of an individual organism (human, animal, plant, microbe, etc.) that was not inherited from its parents. This type of mutation spontaneously occurs during the process of DNA replication during cell division. De novo mutations, by definition, are present in the affected ...
Piebaldism has been documented to occur in all races, and is found in nearly every species of mammal. The condition is very common in mice, rabbits, dogs, sheep, deer, cattle and horses—where selective breeding has increased the incidence of the mutation—but occurs among chimpanzees and other primates only as rarely as among humans.