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Epinephrine is also used as a bronchodilator for asthma if specific β 2 agonists are unavailable or ineffective. [39] Because of the high intrinsic efficacy (receptor binding ability) of epinephrine, high drug concentrations cause adverse side effects when treating asthma. The value of using nebulized epinephrine in acute asthma is unclear. [40]
An epinephrine autoinjector (or adrenaline autoinjector, also known by the trademark EpiPen) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It is most often used for the treatment of anaphylaxis. The first epinephrine autoinjector was brought to market in 1983.
The US Food and Drug Administration approved the first nasal spray epinephrine drug for severe allergic reactions known as anaphylaxis, providing a needle-free alternative to EpiPens and similar ...
Side effects during sublingual immunotherapy treatment are usually local and mild and can often be eliminated by adjusting the dosage. [7] Anaphylaxis during sublingual immunotherapy treatment has occurred on rare occasions. [7] Potential side effects related to subcutaneous immunotherapy treatment for asthma and allergic rhinoconjunctivitis ...
The US Food and Drug Administration on Friday approved a medication called Xolair to help lessen the severity of an accidental allergic reaction in people who are allergic to multiple foods.
The nasal spray Neffy is the first non-injectable epinephrine to treat the life-threatening allergic response EpiPen Alternative for Anaphylaxis Approved by FDA — No Needles Skip to main content
However, the serotonin receptor antagonism has side effects such as weight gain and impaired movement. [11] Hence, alpha-2 blockers are not used clinically due to its extensive binding. Similar to the alpha-1 blocker, the alpha-2 family will also present the first-dose effect , but it is generally less pronounced compared with the alpha-1 blockers.
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.