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Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, [7] is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1]
Since they were previously exposed, the immune system’s memory T cells quickly release cytokines to try and control the new outbreak, which forms more areas of caseous necrosis, this time, though, it tends to cavitate, or form cavities, which can allow the bacteria to disseminate, or spread through airways and lymphatic channels to other ...
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
An infectious disease agent can be transmitted in two ways: as horizontal disease agent transmission from one individual to another in the same generation (peers in the same age group) [3] by either direct contact (licking, touching, biting), or indirect contact through air – cough or sneeze (vectors or fomites that allow the transmission of the agent causing the disease without physical ...
Bacteria enter the body through inhalation and are ingested by white blood cells called macrophages. [1] Surviving bacteria multiply and can spread to other areas of the body. This can occur through the lymphatic system , blood, or via direct spread from infected tissues.
Tuberculosis can also spread through the blood from the primary focus to elsewhere in the abdomen. Abdominal solid organs, kidneys, lymph nodes and peritoneum can be affected this way. [ 2 ] Tuberculosis is also reported to spread to the peritoneum directly from adjacently situated infected foci, such as from the fallopian tubes, adnexa, psoas ...
Respiratory droplet transmission is the usual route for respiratory infections. Transmission can occur when respiratory droplets reach susceptible mucosal surfaces, such as in the eyes, nose or mouth. This can also happen indirectly via contact with contaminated surfaces when hands then touch the face. Respiratory droplets are large and cannot ...
The following outline is provided as an overview of and topical guide to concepts related to infectious diseases in humans.. Infection – transmission, entry/invasion after evading/overcoming defense, establishment, and replication of disease-causing microscopic organisms (pathogens) inside a host organism, and the reaction of host tissues to them and to the toxins they produce.