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  2. Genetic correlation - Wikipedia

    en.wikipedia.org/wiki/Genetic_correlation

    A genetic correlation of 0 implies that the genetic effects on one trait are independent of the other, while a correlation of 1 implies that all of the genetic influences on the two traits are identical. The bivariate genetic correlation can be generalized to inferring genetic latent variable factors across > 2 traits using factor analysis ...

  3. Nutritional genomics - Wikipedia

    en.wikipedia.org/wiki/Nutritional_genomics

    Nutritional genomics, also known as nutrigenomics, is a science studying the relationship between human genome, human nutrition and health. People in the field work toward developing an understanding of how the whole body responds to a food via systems biology, as well as single gene/single food compound relationships.

  4. Gene–environment correlation - Wikipedia

    en.wikipedia.org/wiki/Gene–environment_correlation

    Twin and adoption studies have provided much of the evidence for gene–environment correlations by demonstrating that putative environmental measures are heritable. [5] For example, studies of adult twins have shown that desirable and undesirable life events are moderately heritable as are specific life events and life circumstances, including divorce, the propensity to marry, marital quality ...

  5. Gene-environment interplay - Wikipedia

    en.wikipedia.org/wiki/Gene-environment_interplay

    Gene–environment interaction occurs when genetic factors and environmental factors interact to produce an outcome that cannot be explained by either factor alone. [6] For example, a study found that individuals carrying the genetic variant 5-HTT (the short copy) that encodes the serotonin transporter were at a higher risk of developing depression when exposed to adverse childhood experiences ...

  6. Thrifty gene hypothesis - Wikipedia

    en.wikipedia.org/wiki/Thrifty_gene_hypothesis

    Prentice et al. [17] predicted that the emerging molecular genetics field would ultimately provide a way to test between the adaptive 'thrifty gene' idea and the non-adaptive 'drifty gene' idea because it would be possible to find signatures of positive selection in the human genome, at genes that are linked to both obesity and type 2 diabetes ...

  7. Pleiotropy - Wikipedia

    en.wikipedia.org/wiki/Pleiotropy

    Photomicrograph of normal-shaped and sickle-shape red blood cells from a patient with sickle cell disease. Sickle cell anemia is a genetic disease that causes deformed red blood cells with a rigid, crescent shape instead of the normal flexible, round shape. [29] It is caused by a change in one nucleotide, a point mutation [30] in the HBB gene.

  8. Epigenetics - Wikipedia

    en.wikipedia.org/wiki/Epigenetics

    Epigenetic mechanisms. In biology, epigenetics is the study of heritable traits, or a stable change of cell function, that happen without changes to the DNA sequence. [1] The Greek prefix epi-(ἐπι-"over, outside of, around") in epigenetics implies features that are "on top of" or "in addition to" the traditional (DNA sequence based) genetic mechanism of inheritance. [2]

  9. Genetic interaction network - Wikipedia

    en.wikipedia.org/wiki/Genetic_interaction_network

    The majority of genes do not code for particular phenotypes. Instead, phenotypes often result from the interaction between several genes. In humans, "Each individual carries ~4 million genetic variants and polymorphisms, the overwhelming majority of which cannot be pinpointed as the single cause for a given phenotype. Instead, the effects of ...

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