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Preliminary research indicates that prolonged exposure to high doses of THC may interfere with chromosomal stability, which may be hereditary as a factor affecting cell instability and cancer risk. The carcinogenicity of THC in the studied populations of so-called "heavy users" remains dubious due to various confounding variables, most ...
Cannabis and cancer risk. The cannabis plant contains more than 100 cannabinoids, including THC and CBD, and hundreds of non-cannabinoid chemicals. Scientists are just beginning to understand the ...
Causes of head and neck cancers. In the United States, head and neck cancers make up 4% of all cancers, with more than 71,000 new cases and more than 16,000 deaths expected in 2024, according to ...
The temporal relationship between cannabis and psychosis was reviewed in 2014, and the authors proposed that "[b]ecause longitudinal work indicates that cannabis use precedes psychotic symptoms, it seems reasonable to assume a causal relationship" between cannabis and psychosis, but that "more work is needed to address the possibility of gene ...
Cannabinoid production starts when an enzyme causes geranyl pyrophosphate and olivetolic acid to combine and form CBGA. Next, CBGA is independently converted to either CBG, THCA, CBDA or CBCA by four separate synthase, FAD-dependent dehydrogenase enzymes. There is no evidence for enzymatic conversion of CBDA or CBD to THCA or THC.
Cannabis (/ ˈ k æ n ə b ɪ s /), [2] commonly known as marijuana (/ ˌ m æ r ə ˈ w ɑː n ə /), [3] weed, and pot, among other names, is a non-chemically uniform drug from the Cannabis plant. Native to Central or South Asia, cannabis has been used as a drug for both recreational and entheogenic purposes and in various traditional ...
THCA synthase is expressed in the glandular trichomes of Cannabis sativa. THCA synthase may contribute to the self-defense of Cannabis plants by producing THCA and hydrogen peroxide, which are both cytotoxic. Because these products are toxic to the plant, THCA synthase is secreted into the trichome storage cavity. [7]
The legalization of recreational cannabis in a number of states is associated with the increasing problem of acute cannabis intoxication (ACI). Data gathered by the Nationwide Emergency Department ...