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Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth, often in the form of hydroxychloroquine sulfate. [3]
Hydroxychloroquine is taken at daily dosages of 5 or more mg per kilogram (i.e., kg) of patient weights per day but not exceeding a total of 400 mg per person per day. [8] [65] Individuals treated with hydroxychloroquine at dosages less than 6.5 mg per kg of body weight per day rarely develop retinal injury. [1]
A World Health Organization infographic that states that hydroxychloroquine does not prevent illness or death from COVID-19. Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [64] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [65]
Quinine is a medication used to treat malaria and babesiosis. [5] This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available.
Add some spice to your cooking with these vibrant and satisfying recipes featuring turmeric.This golden rhizome features a compound called curcumin, which is known to help fight inflammation ...
One such cocktail – hydroxychloroquine combined with a high dose of zinc (as a sulfate, 220 mg (50 mg elemental Zn) per day for five days, a zinc dose ~4 times higher than the reference daily intake level) [63] and an approved antibiotic, either azithromycin or doxycycline – began in May as a Phase IV trial in New York State. [65]
The risk of toxicity is low for individuals without complicating conditions during the first five years of treatment using less than 6.5 mg/kg/day of hydroxychloroquine or 3 mg/kg/day of chloroquine, and/or cumulative doses of less than 1000 gram and 460 gram (total dose), respectively.
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