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General signs and symptoms include depression, fever, weight loss, loss of appetite, loss of hair or fur and vomiting. Lymphoma is the most common cancerous cause of hypercalcemia (high blood calcium levels) in dogs. [9] It can lead to the above signs and symptoms plus increased water drinking, increased urination, and cardiac arrhythmias.
Carcinoembryonic antigen (CEA) describes a set of highly-related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Consequently, CEA is usually present at very low levels in the blood of healthy adults (about 2–4 ng/mL). [2]
Dogs are one of three mammalian species that are known to suffer from a transmissible cancer. [7] Canine transmissible venereal tumor (CTVT) is species specific and highly contagious. [ 7 ] The cancerous cell lines are transmitted between individuals that are in close contact with each other through acts of intercourse, biting, scratching, or ...
uric acid > 8 mg/dL or 25% increase; potassium > 6 meq/L or 25% increase; phosphate > 4.5 mg/dL or 25% increase; calcium < 7 mg/dL or 25% decrease; Clinical tumor lysis syndrome: laboratory tumor lysis syndrome plus one or more of the following: increased serum creatinine (1.5 times upper limit of normal) cardiac arrhythmia or sudden death; seizure
Dogs rarely show symptoms of hemangiosarcoma until after the tumor ruptures, causing extensive bleeding. Then symptoms can include short-term lethargy, loss of appetite, enlarged abdomen, weakness in the back legs, paled colored tongue and gums, rapid heart rate, and a weak pulse. [19]
CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2] These symptoms can impair activities of daily living, such as typing or dressing, reduce balance, and increase risk of falls and hospitalizations. They can also give cause to reduce or discontinue chemotherapy.
Symptoms include liver and kidney failure and vasculitis. [10] Lyme disease* is a disease caused by Borrelia burgdorferi, a spirochaete, and spread by ticks of the genus Ixodes. Symptoms in dogs include acute arthritis, anorexia and lethargy. There is no rash as is typically seen in humans. [11]
The symptoms depend on the tumor's location and degree of invasion. For example, tumors in the gastrointestinal tract may cause vomiting, diarrhea, or weight loss. Tumors in the mouth may cause bad breath, difficulty swallowing, or lack of appetite. Tumors arising in the peripheral nerves may cause pain, lameness, or neurological symptoms.