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In molecular biology and genetics, DNA annotation or genome annotation is the process of describing the structure and function of the components of a genome, [2] by analyzing and interpreting them in order to extract their biological significance and understand the biological processes in which they participate. [3]
The translation table list below follows the numbering and designation by NCBI. [2] Four novel alternative genetic codes were discovered in bacterial genomes by Shulgina and Eddy using their codon assignment software Codetta, and validated by analysis of tRNA anticodons and identity elements; [ 3 ] these codes are not currently adopted at NCBI ...
Biological databases are stores of biological information. [1] The journal Nucleic Acids Research regularly publishes special issues on biological databases and has a list of such databases. The 2018 issue has a list of about 180 such databases and updates to previously described databases. [2]
The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. [1] More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for easy access ...
The CCDS dataset is an integral part of the GENCODE gene annotation project [11] and it is used as a standard for high-quality coding exon definition in various research fields, including clinical studies, large-scale epigenomic studies, exome projects and exon array design. [3] Due to the consensus annotation of CCDS exons by the independent ...
View all annotations created for a gene, for example pat1; View all genes annotated a term, for example cytokinesis; View all annotations created from a specific reference, for example 26776736 Chica et al. 2016; Genome-wide datasets (including protein datasets, all annotations, manually curated ortholog lists etc) can be accessed from the ...
Saccharomyces cerevisiae was the first eukaryotic organism to have its complete genome sequence determined.. This list of "sequenced" eukaryotic genomes contains all the eukaryotes known to have publicly available complete nuclear and organelle genome sequences that have been sequenced, assembled, annotated and published; draft genomes are not included, nor are organelle-only sequences.
MANE (Matched Annotation from the NCBI and EMBL-EBI): It is a collaborative project between NCBI and EMBL-EBI whose main goal is to define a set of transcripts and their proteins for all the protein-coding genes in the human genome. By doing that, the differences in transcripts annotation between RefSeq and Ensembl/GENCODE annotation systems ...