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Philidor Rx Services is a Pennsylvania-licensed specialty online pharmacy, which mainly sold [4] [5] Valeant Pharmaceuticals International Inc drugs directly to patients and handled insurance claims on the customers' behalf. [1] [6]
Tretinoin (retinoic acid)causes dispersion of pigment granules in keratinocytes,interferes with pigment transfer,and acceler-ates epidermal transfer,thus causing pigment to be lost more rapidly.Tretinoin also accelerates epidermal turnover,shorten-ing the "transit time"from the basal layer and accelerating pig-ment loss.Retinoic acid reduces ...
The name isotretinoin is the same root tretinoin plus the prefix iso-. Regarding pronunciation, the following variants apply equally to both tretinoin and isotretinoin. Given that retinoic is pronounced / ˌ r ɛ t ɪ ˈ n oʊ ɪ k /, [43] [44] [42] [45] it is natural that / ˌ t r ɛ t ɪ ˈ n oʊ ɪ n / is a commonly heard pronunciation.
Insurance companies have generally been willing to pay high prices for such drugs; since few of their customers need the drugs, a high price does not significantly impact the insurance companies outlays. [76] Alexion is thus seeking a stronger position in the lucrative rare disease market, and is willing to pay a premium to obtain that position.
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Tretinoin/benzoyl peroxide, sold under the brand name Twyneo, is a fixed-dose combination medication used for the treatment of acne. [1] [2] It contains tretinoin, a vitamin A derivative, and benzoyl peroxide, an oxidizing agent. [3] The combination was approved for medical use in the United States in July 2021. [2] [4] [5]
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Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]
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