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[1] [3] [5] Originally thought to selectively act on serotonin, PBMA was subsequently found to act not only on serotonin but also on norepinephrine and dopamine similarly to PCA. [4] [6] [7] It has been reported to produce pharmacological effects that have been said to be "somewhat similar" or "indistinguishable" to those of lysergic acid ...
para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects. Another related compound is para-bromomethamphetamine (PBMA) known by the codename V-111. [1]
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para-Chloromethamphetamine (also known as 4-chloromethamphetamine and 4-CMA) is a stimulant that is the N-methyl derivative and prodrug of the neurotoxic drug para-chloroamphetamine (4-CA). [ 1 ] [ 2 ] It has been found to decrease serotonin in rats.
4-Fluoroamphetamine is a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine. [9] The respective EC 50 values are 2.0 x 10 −7 M, 7.3 x 10 −7 M, and 0.37 x 10 −7 M, while the IC 50 values are 7.7 x 10 −7 M, 68 x 10 −7 M, and 4.2 x 10 −7 M. [3]
In animals, doses of PCA of 0.5 to 5 mg/kg acutely produce a variety of behavioral and neurochemical effects thought to be due to serotonin release. [3] [19] [20] Consequent enhancement of serotonergic signaling, serotonergic effects like myoclonus, the serotonin behavioral syndrome, including tremor, rigidity, Straub tail, hindlimb abduction, lateral head weaving, and reciprocal forepaw ...
4-Bromomethcathinone (4-BMC, Brephedrone) is a psychoactive drug and research chemical of the phenethylamine, amphetamine, and cathinone chemical classes. It acts as a serotonin and norepinephrine reuptake inhibitor , [ 1 ] [ 2 ] but acts more like an antidepressant than a stimulant . [ 3 ]
para-Methoxymethamphetamine (PMMA), also known as 4-methoxy-N-methylamphetamine (4-MMA), is a serotonergic drug of the amphetamine family related to para-methoxyamphetamine (PMA). It is the 4- methoxy analogue of methamphetamine .